Infertility in Systemic Lupus Erythematosus

for queries regarding Infertility treatment,

 Dr Deepika Tiwari; Consultant Obstetrician &
Gynaecologist, Sohna Road,Gurgaon 9911821669

SLE is a multi-system, autoimmune condition that can influence

both male and female fertility. Inability to conceive may be

attributed to several factors that may act singly or in

combination: (i) older age in patients with SLE compared with

healthy controls; (ii) disease-related infertility; and (iii) infertility

through gonadotoxic treatments. In addition, psychosocial factors

related to the disease may lower fecundity and may be associated

 with apparent infertility. Many therapeutic avenues are open to

 counteract reproductive damage in the management of SLE and

to assist conception once infertility is diagnosed. These treatments

 can include the administration of gonadotrophin-receptor

hormone analogues while receiving Cyclophosphamide (CYC)

 treatment, the use of assisted reproductive technologies, such

as in vitro fertilization and psychosocial intervention to promote a

 healthier relationship with their partner.